Cancer biology explores the complex ways cells grow out of control, investigating the genetic mutations and environmental factors that drive tumor formation. This field seeks to understand how healthy cells transform into malignant ones and how these rogue cells spread throughout the body. By decoding these fundamental mechanisms, researchers aim to develop more effective treatments that target the disease at its source while sparing healthy tissue.

At Gist.Science, we process every new preprint published in this category directly from bioRxiv to ensure you stay ahead of the curve. Our team provides both accessible plain-language overviews and detailed technical summaries for each study, bridging the gap between raw research data and practical understanding. Whether you are a specialist or a curious reader, our goal is to make these critical findings clear and actionable.

Below are the latest papers in cancer biology, offering fresh insights into the ongoing fight against this disease.

Nerve Injury-Induced Protein 2 Is Necessary for the Lysosome Membrane Integrity and Protects Cells from Ferroptosis

This study identifies that NINJ2 maintains lysosomal membrane integrity by interacting with LAMP1, thereby preventing the leakage of labile iron and the degradation of ferritin, a mechanism that protects cells from ferroptosis and presents a potential therapeutic target for iron-addicted cancers.

Zhang, J., Bustamante, M., Shi, Y., Nakajima, K.-i., Chen, X.2026-02-11📄 cancer biology